April 13, 2026
The Incubator Podcast

Prof Brett Manley, co–Chief Principal Investigator for PLATIPUS, flew the flag for adaptive platform trials in the latest episode of 'The Incubator Podcast'.

In this latest episode of 'The Incubator Podcast', hosts Ben and Daphna sit down with PLATIPUS's very own Professor Brett Manley to discuss a paradigm shift in neonatal research: adaptive platform trials.

Frustrated by the inefficiencies and underpowered results of traditional RCTs, Prof. Manley outlines the ambitious PLATIPUS Adaptive Platform Trial launching in Australia and New Zealand. They dive into how shared primary outcomes, novel consent models, and massive cross-center collaboration can answer pressing clinical questions—like optimal PPROM antibiotics and caffeine dosing—simultaneously. Tune in for a fascinating conversation on how moving beyond medical dogma, embracing humility, and keeping families at the center of NICU research is helping to improve health outcomes for babies born preterm.

Watch via the YouTube link below, or listen wherever you get your podcasts.

Platform for Adaptive Trials in Perinatal Units

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